IIT-Madras has launched a cancer genome and tissue bank, aiming to take personalized cancer therapy in India to a new level. Scientists are testing therapies on cultured tumor samples, identifying Indian-specific genetic mutations, and developing early detection markers. Supported by the Bharat Cancer Genome Atlas (BCGA), the initiative focuses on delivering precise, affordable, and tailored cancer treatments for Indian patients.
Revolutionizing Cancer Research
Cancer remains one of the deadliest diseases worldwide, and India is experiencing a steady rise in cases. The demand for therapies based on genetic profiles unique to Indian patients is growing. The IIT-Madras project collects around 7,000 tumor samples from patients across the country through the National Cancer Tissue Biobank. These samples are grown in the lab, allowing researchers to test treatments before administering them to patients, reducing guesswork and improving outcomes.
A major discovery includes a breast cancer mutation more common among Indian patients than in Western populations. This highlights the need for India-focused genetic research, as therapies developed solely using Western data may not be fully effective for Indian patients.
Focus on Early Detection and Pancreatic Cancer
Beyond breast cancer, IIT-Madras scientists are developing genetic panels for pancreatic cancer, combining global and Indian data to identify markers for early diagnosis. Early detection is particularly critical for pancreatic cancer, which is difficult to treat once advanced. Researchers are also investigating blood-based markers to improve survival rates.
Bharat Cancer Genome Atlas: A Key Resource
The initiative is complemented by the Bharat Cancer Genome Atlas (BCGA), which holds genomic data from 480 breast cancer patients nationwide. This open-access database provides insights into mutations specific to Indian cases, accelerating the development of targeted diagnostics and therapies.
Towards Precision Medicine in India
By integrating patient-specific genetic and molecular profiles, IIT-Madras is moving India’s cancer treatment toward precision medicine. This approach promises more effective therapies, earlier diagnosis, and improved patient care. Collaborations with healthcare facilities like Karkinos Healthcare and Chennai Breast Clinic, along with government support, are helping make treatments affordable and accessible.
A Hope for Indian Cancer Patients
The IIT-Madras initiative offers hope to millions of patients, transforming research, diagnostics, and therapy development in India. Ongoing work aims to revolutionize cancer treatment, ultimately saving lives and improving the quality of life for patients across the country.
