For millions with diabetes, the daily pain of finger-prick blood tests may soon be a thing of the past. Researchers at the Indian Institute of Science (IISc) Bengaluru have developed a revolutionary, non-invasive glucose monitoring technique. Instead of drawing blood, this method uses photoacoustic sensing, which relies on laser beams and sound waves to measure glucose levels.

How the Technology Works
When a laser beam shines on biological tissue, the absorbed light causes a slight expansion, generating tiny sound waves. Researchers found that glucose alters the intensity of these waves, allowing them to estimate blood sugar levels accurately. The technique was successfully tested on glucose solutions, animal tissue samples, and even a human participant, proving its potential.

Challenges and Future Prospects
Although the method shows promise, commercial use is still a challenge due to the high cost and bulky size of the laser setup. Scientists are now working on miniaturizing and making the system more affordable. If successful, this innovation could pave the way for portable, painless glucose monitors, eliminating the need for finger pricks.
Beyond diabetes, this photoacoustic sensing method could also be applied to detect other chiral molecules, such as drugs and biomarkers, opening new possibilities in medical diagnostics.